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Reversible Signal Abnormalities in the Hippocampus and Neocortex after Prolonged Seizures AJNR 17:1725-1731, Chan,S.,et al, 1996 See this aricle in Pubmed Article Abstract All six MR studies showed increased signal intensity within the median temporal lobe including the hippocampus in five studies.All followup MR examinations showed partial or complete resolution of the hyperintensity within the medial temporal lobe and the neocortex.In one patient,results of a brain biopsy revealed severe cerebral cortical gliosis.Temporal lobectomy performed 4 years later showed moderate cortical gliosis and nonspecific hippocampal cell loss and gliosis.Significant hyperintensity within the temporal lobe is demonstrable on MRI images after prolonged seizure activity suggestive of seizure-induced edema or gliosis.Damage to medial temporal lobe structures by prolonged seizure activity indicates a possible mechanism of epileptogenic disorders.

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(click to filter results - removes previous filter) hippocampus mesial temporal sclerosis MRI MRI,abnormal MRI,abnormal,seizure causing MRI,disappearing lesion on MRI,gyral enhancement seizure seizure,complications following temporal lobe temporal lobe,lesion

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